Free cortisol and the dexamethasone suppression test
نویسندگان
چکیده
منابع مشابه
Association between posttest dexamethasone and cortisol concentrations in the 1 mg overnight dexamethasone suppression test
It has been suggested that comparison of posttest dexamethasone and cortisol concentrations may improve the evaluation of the dexamethasone suppression test (DST) for Cushing's syndrome. In particular, this would be reasonable if posttest cortisol differs by dexamethasone levels within the range that is usually attained in the DST. Using fractional polynomial regression, we therefore studied th...
متن کاملComparison of plasma cortisol and corticosterone in the dexamethasone suppression test for melancholia.
The suppression of plasma corticosterone (B), measured by radioimmunoassay (RIA), was compared to simultaneous suppression of plasma cortisol (F), measured as total corticoids by a competitive protein binding (CPB) assay, in the overnight dexamethasone suppression test (DST). Baseline plasma B concentrations in 10 control subjects were 4.04 +/- 1.07 ng/ml (X +/- S.D.) at 0800 hr and 1.51 +/- 0....
متن کاملDexamethasone Suppression Test in Depression
Baseline plasma Cortisol levels and response to dexamethasone in a group of twenty five patients with ma) or depressive disorder (MDD) and a control group of twenty five patients with psychiatric diagnoses other than MDD were estimated. The results of our study show that dexamethasone suppression test (DST) is a useful diagnostic aid in MDD with melancholia with a sensitivity of 46% and specifi...
متن کاملPlasma dexamethasone levels in children given the dexamethasone suppression test.
To determine whether children who demonstrate dexamethasone suppression test (DST) nonsuppression have lower plasma dexamethasone levels than DST suppressors, we administered the DST to 73 patients ranging in age from 5-14 years. Plasma dexamethasone levels and postdexamethasone cortisol levels were measured at 4:00 PM on day 2. We found: (1) DST nonsuppressors had significantly lower plasma de...
متن کاملElevated Cortisol Level and Cortisol/DHEAS Ratio in Schizophrenia as Revealed by Low-Dose Dexamethasone Suppression Test
Earlier studies have used the dexamethasone (DEX) suppression test (DST) to investigate the hypothalamicpituitary-adrenal (HPA) function in schizophrenia, although the findings are controversial. Recently there has been an increased interest in the role of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) in HPA axis function. Several studies have investigated basal DHEA(S) levels and corti...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 1986
ISSN: 0006-3223
DOI: 10.1016/0006-3223(86)90199-x